Endocrine Abstracts

Can we drug receptors for microbially-produced metabolic hormones and for what indications? G protein-coupled receptors (GPCRs) have been a major group of druggable cell surface receptors and therapeutics targeting many hormone-activated GPCRs have been developed. A number of products of the processing and metabolism of foodstuffs act in a hormone-like manner and these include both short and medium chain length free fatty acids. Short chain fatty acids produced in large amount...